AXOS

Not all prebiotic dietary fibers are the same.

Prebiotic fibers offer a solution to help the food and beverage industry develop products with reduced sugar, fewer calories, and a functional ingredient boost. Unfortunately, many popular prebiotic fiber options require high inclusion levels to be effective. For example, 5 grams or more is needed for inulin, a commonly used prebiotic fiber derived from chicory root. These higher inclusion rates render many confectionery applications impractical. Several popular prebiotic fiber options, including inulin, are also oligosaccharides, a type of fiber that the popular low-FODMAP diet cautions individuals to avoid due to tolerability concerns.

A new class of premium prebiotic fibers is now coming to market with lower inclusion rates and better tolerability to address these concerns. These novel prebiotics are from different families of fibers, including long-chain polysaccharides, resistant starches, and polyphenols. These prebiotic fibers are tailored to offer functional benefits while being more versatile and easier to incorporate.

COMET’s Arrabina is an Arabinoxylan and AXOS Prebiotic fiber. It is a hemicellulose polysaccharide fiber with clinically proven prebiotic benefits. The fiber’s longer chain polysaccharide structure makes it better tolerated by the gut than oligosaccharides. Results from COMET’s recent clinical trial revealed that consumers could take up to 15 grams per day of Arrabina with no adverse stomach or bowel reaction. Arrabina also boasts superior potency with sufficient inclusion levels as low as 3.4 grams and is cost-effective compared to other prebiotic fiber options.

At COMET, we believe the Arabinoxylan and AXOS are Nature’s Best Dietary Fiber. Arabinoxylan (AX) is a well-known and scientifically studied hemicellulose polysaccharide prebiotic fiber found in many plants; bran, husks, and shells.  It consists of a linear backbone of β-1,4 xylose residues with arabinose substitution. The xylose units are substituted with 2 arabinose residues at some of the O-2, O-3 or both the O-2 and O-3 positions.

Several additional clinical trials have documented the effects of AX on the selective growth of bifidobacterial in the gut (Windley et al. 2015, Cloetens et al. 2010, Francois et al. 2014, Maki et al. 2012, Walton et al. 2012, Damen et al. 2012, Kjølbæk et al. 2019). Several of the trials also reported altered fermentation in the colon, including reduction of protein fermentation (Windley et al. 2015, Francois et al. 2014), reduced urinary p-cresol excretion14) and an increase in short-chain fatty acids (SCFA) in the gut which is a marker of bacterial fermentation (Francois et al. 2014, Walton et al. 2012, Damen et al. 2012, Salden et al. 2018).

References:

  • Current Developments in Nutrition, Volume 5, Issue Supplement_2, June 2021, Page 304,https://doi.org/10.1093/cdn/nzab037_014
  • Windey et al. 2015. Wheat bran extract alters colonic fermentation and microbial composition, but does not affect faecal water toxicity: a randomised controlled trial in healthy subjects. British Journal of Nutrition, 113, 225-238.
  • Cloetens et al. 2010. Tolerance of arabinoxylan-oligosaccharides and their prebiotic activity in healthy subjects: a randomised, placebo-controlled crossover study. British Journal of Nutrition, 103, 703-713.
  • François IE, Lescroart O, Veraverbeke WS, Marzorati M, Possemiers S, Hamer H, Windey K, Welling GW, Delcour JA, Courtin CM, Verbeke K, Broekaert WF. Effects of wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal parameters in healthy preadolescent children. J Pediatr Gastroenterol Nutr. 2014 May;58(5):647-53.
  • Maki KC, Gibson GR, Dickmann RS, Kendall CW, Chen CY, Costabile A, Comelli EM,McKay DL, Almeida NG, Jenkins D, Zello GA, Blumberg JB. Digestive and physiologic effects of a wheat bran extract, arabino-xylan-oligosaccharide, in breakfast cereal. Nutrition. 2012 Nov-Dec;28(11-12):1115-21.
  • Walton GE, Lu C, Trogh I, Arnaut F, Gibson GR. A randomized, double-blind, placebo-controlled cross-over study to determine the gastrointestinal effects of consumption of arabinoxylan-oligosaccharides enriched bread in healthy volunteers. Nutr J. 2012 Jun 1;11:36.
  • Kjølbæk, L., Benítez-Páez, A., Pulgar, E. M., Brahe, L. K., Liebisch, G., Matysik, S., . . . Sanz, Y. (2019). Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: A randomized cross-over trial. Clinical Nutrition. doi:10.1016/j.clnu.2019.01.012
  • Windey K, François I, Broekaert W, De Preter V, Delcour JA, Louat T, Herman J, Verbeke K. High dose of prebiotics reduces fecal water

Low dose prebiotic fiber

With as little as 3 grams per day, Arrabina® promotes growth of beneficial bifidobacteria2

PREBIOTIC EFFECTIVE LEVEL
ARRABINA®
OTHER PREBIOTIC FIBERS

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ARRABINA®'s
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